Microflora of Digestive Tract in Poultry

Molecular Approaches for the Study of Genetic Diversity in Microflora of Poultry Gastrointestinal Tract

Proteolytic bacteria in the lower digestive tract of poultry may affect avian influenza virus pathogenicity.

Proteolytic cleavage of hemagglutinin is required for cell entry by receptor-mediated endocytosis and plays a key role in pathogenicity of the influenza virus. Despite several studies describing relationships between bacterial proteases and influenza A viral activation in mammals, very little is known about the role of the normal bacterial flora of birds on hemagglutinin activation. We examined...

Intestinal microflora and digestive toxicity of irinotecan in mice.

PURPOSE Delayed diarrhea is the most important side effect of irinotecan. The aim of this study was to investigate the role of intestinal microflora on the induction of systemic and intestinal toxicity and diarrhea, studying germ-free and holoxenic mice i.p. injected with irinotecan. EXPERIMENTAL DESIGN To evaluate the lethal dose, starting with 100 mg/kg/4 d, we treated the holoxenic mice wi...

Gas in the Digestive Tract

Lower Digestive Tract

This small book is an attempt to review present knowledge on the morphology, immunology, and pathogenicity of the pleuropneumonia-like organisms (PPLO). The author is a recognized authority on these organisms and the material is presented from her point of view, although she readily admits that there are some who may be in disagreement with her conclusions. Four of the eleven chapters are devot...